Current projects
We have identified a transcription factor NF1-C2 that we think is important for normal mammary gland development. Therefore, will we further analyze this factor and its involvement in the proliferation and the development of mammary epithelial cells. We will also identify other targets that are regulated by this factor.
Although CEL may have its primary role in the intestine, low amounts of CEL are also present in the circulation. Neither the role of this circulating CEL, nor its sources are yet defined. To answer these questions we have outlined a project that will address the issue of where CEL is present and where it may be produced.